Human eyes are among the tiniest organs in the body. They are, however, two of the most important organs for many people, because sight is the sense on which humans rely the most.
While it is true that the human body is one big machine in which nothing acts independently of everything else, there are surprisingly few organs that work in direct concert with the eyes.
There must be light in order for people to see. Light enters the eye, which focuses the refracting light from the environment and allows us to perceive shape, color, distance, and so on.
The light is then transmitted to the brain via nerve signals along the optic nerve. The images received by the eyes are interpreted and used in the human brain to form an impression of the world around us.
The brain, obviously, is the main organ that works with the eyes, specifically the visual cortex, which interprets what the eye sees. There are, however, a number of organ systems that work in tandem with the eye.
Because muscle tissue allows the eye to turn and rotate in its socket, the muscular system is linked to the eye. The nervous system is also linked to the eye because the optic nerve transmits visual impressions to the brain. The eyes are linked to the vascular system because they require blood and nutrients to function, but this can be said of any organ in the human body.